LaserVue LASIK & Cataract Center

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Corneal Collagen Cross-Linking

Corneal Collage Cross-Linking DiagramCorneal collagen cross-linking, or CXL, is a revolutionary noninvasive outpatient treatment for progressive keratoconus patients and corneal ectasia patients. LaserVue offers cross-linking treatment to San Francisco and Bay Area keratoconus patients.  This treatment requires nothing more than a riboflavin-containing solution and an ultraviolet light delivery device to strengthen the cornea.  CXL treatments slow or halt progressive keratoconus for about 90% of patients and improve vision in more than half of patients treated.

Besides just San Francisco and the Bay Area, our patients come from all over Northern California to undergo collagen cross-linking for progressive keratoconus.

How is CXL Performed?

First, numbing drops are added to the eyes to ensure patient comfort. Riboflavin solution drops are added to the eye; these drops saturate the cornea in riboflavin for about thirty minutes.  Special cases may necessitate removal of the outermost corneal epithelial cells prior to the addition of riboflavin. Once the eye is thoroughly saturated, the eye is treated with ultraviolet light. This treatment lasts between 5 and 30 minutes.

How Does CXL work?

Ultraviolet light reacts at a molecular level with riboflavin on the surface of the cornea. Resulting bonds, or cross-links, make the cornea stronger. Strengthening the cornea slows, and for many patients stops, progressive keratoconus and corneal ectasia.

Collagen Cross-Linking Benefits

  • Slows or Halts Progressive Keratoconus
  • Requires A Single One-Hour Treatment
  • Zero Injections
  • Zero Stitches
  • Zero Incisions
  • Fast Recovery

Collagen Cross-Linking Candidacy

  • 14 Years of Age or Older
  • Prior Diagnosis of Progressive Keratoconus or Corneal Ectasia
  • Adequate Corneal Thickness
  • Not Be Pregnant
  • Ability to Leave Contact Lenses Out for Four Weeks Before and After Treatment

Get the Cross-Linking FAQ’s

To learn more about keratoconus, please call 800.527.3745 to make an appointment to see one of our specialists at LaserVue Eye Center. LaserVue Eye Center is also a leading provider of cataract surgery and laser vision correction in San Francisco Bay Area.


1700 California St., #480,
San Francisco, CA 94109
Location & Map 1-800-527-3745 1-415-346-5500

3540 Mendocino Ave. #200,
Santa Rosa, CA 95403
Location & Map 1-800-527-3745 1-707-522-6200

1174 Castro St., #112,
Mountain View, CA 94040
Location & Map 1-800-527-3745 1-650-966-0900

108 La Casa Via. Suite 104,
Walnut Creek, CA 94598
Location & Map 1-800-527-3745 1-925-947-2020